Say goodbye to ineffective hair creams and useless lotions, losing hair may be a thing of the past!

Thanks to a group of researchers from Seoul, the balding affect that was synonymous with a later stage in life, might be out the window.

A group from Yonsei University in Seoul claims to have formed and found a novel biochemical agent that prevents hair loss.

The researchers, which are led by a man called Choi Kang-Yeol, even went as far as to say the formula, which they titled PTD-DMB, promotes the growth of new hair.

The team lead by Choi discovered that the reason behind lost hair not regrowing is that two different proteins, CXXC5, and another protein, are found on the scalp, and they interact in a way which prevents the regeneration of hair follicles.

The wondrous PTD-DMB formulated by the group prevents the two proteins from binding, which enables new hair growth – as well as promotes it.

The Journal of Investigative Dermatology’s November issue included a paper titled “Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis.”

The Seoul-based researchers revealed their findings:

“Disrupting the CXXC5-Dishevelled interaction with a competitor peptide activated the Wnt/β-catenin pathway and accelerated hair regrowth and wound-induced hair follicle neogenesis. Overall, these findings suggest that the CXXC5-Dishevelled interaction is a potential target for the treatment of hair loss.”

Currently, the team is testing PRD-DMB for toxicity. South Korean media is following the process, ready to expose the new revelations as soon as they are found.

“We have found a protein that controls the hair growth and developed a new substance that promotes hair regeneration by controlling the function of the protein. We expect that the newly developed substance will contribute to the development of a drug that not only treats hair loss but also regenerates damaged skin tissues,” Choi said.

Celebrity families are the envy of society. These guys mainly make up the largest segment of nouveau riche not just in the United States, but across the globe. With such a reputation, you would expect these families to live happy and contented lives with their wealth and status in society. Unfortunately, peace of mind is often hard to come by even for celebrities. Most times, this is disrupted by their flesh and blood. These 45 celebs are excellent examples of how money and fame don’t necessarily guarantee a happy family.

Brad Pitt and Maddox had a stable relationship until the two found themselves in disagreement while they were on a private plane traveling to Los Angeles in 2016. Pitt is said to have gotten physical after Maddox stepped in to defend his mother.

Maddox later moved to South Korea for college, and while he said the relationship hadn’t improved, he did mention he was open to reconciliation. Pitt and Maddox are rumored to have met in January when Maddox was home for the holidays, but the details of their encounter are unconfirmed.

When Ashton Kutcher and Demi Moore broke up back in 2013, Moore fought very openly with the end of her marriage. It was after this when she started to act erratically, which was too much for her daughter, Rumor Willis to handle.

After some time, Rumor Willis stepped away from her own mother while she worked through her personal issues for a while. Luckily they reconciled and seem to have mended their relationship since.

Tom Cruise is not allowed to have a relationship with Suri, the daughter he had with ex-wife Katie Holmes, due to his affiliation with the Church of Scientology. The two haven’t been spotted together in over 6 years.

Because Suri isn’t a Scientologist, Cruise is forbidden from having a relationship with her. The Mission: Impossible star still has a close relationship with his older children from his former marriage to Nicole Kidman because Isabella and Connor are both Scientologists.

Billy Ray Cyrus was estranged from his daughter Miley Cyrus. Ray Cyrus once told GQ, “Damn show destroyed my whole family,” but he affirmed that he would take his family back and just wants everybody to be safe and happy.

Billy expressed his concern for the well-being of his daughter and wished he could erase everything that happened in a second. At some point, Billy even defended Miley’s ex-boyfriend Patrick Schwarzenegger when he was accused of cheating.

Michael Douglas acknowledges that his parental shortcomings are a direct consequence of some of his son Cameron’s flaws. That made Michael’s watching his son go to a federal prison possibly even more painful. Cameron pleaded guilty for possession, earning him a five-year sentence in 2010.

Michael chose to be positive about his son’s situation. However, he felt it was unjust for his son to spend several years in solitary confinement.

She is arguably one of Hollywood’s most attractive women with a great deal of success in the film industry. With movies such as the Tomb Raider series and recent releases like Maleficent, Angelina Jolie is truly at the top of her game. However, her family life isn’t as successful as her entertainment career.

Her father, the world-renown actor Jon Voight, deserted his family when Angelina was still a baby. From then on, their relationship has been far from perfect. She later went on to drop his name [Voight] from hers.

Tom Cruise married Nicole Kidman from 1990-2001, just after his first union to Mimi Rogers ended. While with Kidman, the pair adopted two children and proceeded to raise them according to the Scientology doctrine. Isabella and Connor were set for a life of comfort seeing as how high-profile both parents were.

However, as celebrity families go, keeping it together is a tall order. Once Nicole Kidman left the church in 2001 and divorced Tom, everything fell apart. Their children opted to stay with Dad and in the process, stopped referring to Kidman as their mother. Whatever differences led to their divorce, it sure hurt the family ties.

Charlie Sheen is well-known for his role in the hit comedy series Two and a Half Men, and like his dad before him, the youngest Sheen has made a career for himself in acting. Nevertheless, he had to stand up to addiction more so as a kid.

Martin Sheen never missed punishing the young Sheen on his unpredictable behavior, more so surrounding substance abuse. This has further contributed to widening the rift between the pair of actors.

Another surprising entry on this list is Laurence Fishburne and his daughter. Morpheus, as he is known in the celebrated Matrix Trilogy, is expected to be the model dad, wise and full of life’s experience. However, his daughter Montana Fishburne seems to be on a mission to discredit her father’s reputation.

She has been in adult films, arrested on charges of prostitution and assault, and even went on to work as a stripper. Her actions have damaged her relationship with her famous father as he distances himself from her antics.

Anthony Hopkins starred in BBC’s King Lear adaptation and in 2018, while promoting the film, admitted that he had been out of touch with his daughter. Abigail, Hopkins’ daughter, was abandoned by the actor while still an infant alongside her mother, Petronella Barker.

Hopkins seems to have made peace with the fact that his relationship with Abigail would never be a rosy one. However, he holds no ill-will and even wishes his daughter the best.

Kelly Rutherford’s kids, son Hermes and daughter Helena, have been living with her businessman ex-husband Daniel Giersch since 2012 in France. Since then, Rutherford has been fighting to get them returned to New York.

This was after a judge in California ruled out that despite Giersch and Rutherford sharing custody, their children should continue living with Giersch. Unfortunately, Giersch’s visa was revoked, thus prohibiting him from returning to the U.S, making it much harder for Rutherford to get the kids back.

Eric Roberts is Julia Roberts’ older brother, but you would probably recognize him from the 1985 film Runway Train and the show Brooklyn Nine-Nine. I know this might come as a surprise, but Emma Roberts is Eric’s daughter.

Eric Roberts and Kelly Cunningham, Emma’s mother, never wed, and Eric left when Emma was just a baby. The pair had very little contact until the Scream Queens actress took on Hollywood. “We are now pals,” Eric affirmed this.

Tamra shares a daughter, Sidney, with her ex-husband Simon Barney. They also have two other kids, a son Spencer and a daughter Sophia. But over and over, Tamra and her daughter Sidney have had differences. Tamra Judge recently documented her real struggle with her daughter on The Real Housewives of Orange Country.

This might have been the source of all problem between the two. Reportedly, Sidney doesn’t like the media attention at all, something her mother is quite comfortable with. A short term reconciliation between the two was ruined when Tamra posted a photo on Instagram of them together.

Party animal Steven Tyler is famous for his role in the rock band Aerosmith. With his lifestyle, starting a family seemed like a distant dream, but come 1977, on the first day of July, Liv Tyler was born. She was the only child of model and Playmate Bebe Buell. Sadly, she never got to know her dad up until she was eight.

The Armageddon and Lord of the Rings star had a strained relationship with the famous rocker when he relapsed into drug use. Today, the two maintain limited contact.

Candy Spelling is an American author, theater producer, TV personality, and philanthropist. She was married to fellow acclaimed media personality, Aaron Spelling. The two were married until the producer’s passing in 2006 when he left behind his vast estate to Candy Spelling. This $600 million fortune was initially meant to be shared among his wife and two kids.

However, Candy and daughter Tori hadn’t exactly been seeing eye to eye and this probably inspired Candy’s actions surrounding the wealth sharing. She gave each of her kids less than a million dollars each from Aaron’s immense wealth. It’s pretty hard to miss why these two are conflicting.

Celebrities receive their fame and acclaim from past achievements. Nevertheless, it is the messy stuff that happens behind the scenes that often draws the attention of everyone. For instance, who would’ve thought kung-Fu darling Jackie Chan would be on this list.

Mr. Chan had an affair with former model Elaine Ng which resulted in the birth of his daughter Etta Ng out of wedlock. At the time, he was married to his current wife Joan Lin. Jackie Chan has never acknowledged Etta as his child, at least not in public.

Mr. Jackson’s feud with his kid is probably the most amusing on this list. It all boiled down to a lack of respect from the son to his dad.

Marquise, 50’s son, apparently refused to hold the door open the door for his dad. Because of this minor issue, 50 Cent disowned the boy and asked him never to contact him again. Talk of tough love.

Mia Farrow had a long-drawn battle with former partner, movie director Wood Allen. The two never formally consummated their partnership and went on to adopt kids, Dylan and Ronan Farrow. These two are estranged from their father Woody Allen over sexual abuse allegations.

While she receives support from the two children, things are not as rosy with her other adopted children, Moses and daughter Soon-Yi Previn. The pair stand with their father against the sexual allegations leveled against him by Dylan.

Gavin’s relationship with daughter Daisy Lowe began on a rocky start, to begin with, it seems he wasn’t aware of his daughter’s presence until 2003, just before marrying Gwen Stefani. His previous relationship with British Personality Pearl Lowe had resulted in Gavin’s daughter Daisy, but he wasn’t aware of it until she turned fourteen.

It must have been difficult to realize just how much has been kept from you after the end of a relationship. Gavin swore to keep his distance, seeing as the Lowes had opted to sideline him from their affairs.

Warren Buffet’s immense wealth gives him not only power but also a sort of celebrity status. Mr. Buffet’s life, like others on this list, is always under the media’s scrutiny. In 2006, Warren Buffet shocked the world as he announced not to leave his fortune to any of his children, but rather to charity.

His granddaughter, Nicole Buffet, however, is hardly pleased about the decision. She participated in a follow-up of Born Rich, a documentary on kids born into affluent families in an attempt to reprimand her grandad’s decision to leave her off the will.

The beautiful Sacramento-born Brie Larson came to fame after her appearance in the critically acclaimed Room. However, not many people knew about her tumultuous childhood past. This was until 2016 when she revealed all on Ellen.

Her past family troubles helped her draw strength to reach where she is today. Brie’s parents divorced when she was just ten, and she hardly saw her dad from then on. At twenty-six, she had gone for an entire decade without setting eyes on him.

Kelly Rowland has, for years, wowed us with her glorious voice and hit songs during her time with Destiny’s Child, as well as her solo career. However, behind the success, all was not well at home. During her childhood, her mother left her father, Christopher Lovett on grounds of alcoholism and violence due to PTSD which he suffered after having served in Vietnam.

She moved to Houston when she turned eight and began her music career from there. Kelly and her dad are estranged to this day.

The entertaining Tracy Morgan has had us laughing for a long time now. The actor, comedian, and voice actor, has starred in 30 Rock and Saturday Night Live, among other things. Tracy’s upbringing was normal up to the point when his father abandoned the family.

Jimmy Morgan was a musician and a Vietnam veteran who struggled with addiction. This eventually caused him to leave the family. Tracy himself is not shy to admit his estrangement from much of his family including his mother.

Michael isn’t a thoroughbred celebrity but came to be so after his daughter Lindsay Lohan’s acting success. It is The Parent Trap who introduced Michael to the limelight, after which he dominated tabloids with all manners of scandal. His drug use fueled his decline.

He has humiliated Lindsay several times, trying to profit from her fame and even showing up with cops at her door. Michael is hardly the ideal father and it is no wonder then how no one wants anything to do with him.

Marshall Mathers, or popularly known as Eminem, is probably the most notable celebrity with family issues. Eminem’s hit songs have mostly been full of lyrics exposing his mother as irresponsible. Eminem even admitted to having raised his brother, Nate, all on his own.

However, Debbie Mathers-Briggs fought back with a lawsuit claiming her son slandered her across several media outlets. Debbie asserts that Eminem’s lyrics in his hit-single ‘My name is…’ were made-up and demanded $10 million in compensation—talk of an opportunistic parent.

Adele is another surprising entry on this list. The lovely English singer-songwriter has penned some of the most beautiful tracks to date. She was born to an English mother and her dad was from Wales. Marc Evans, her father, eventually left Adele and her mom, Penny Adkins, when Adele was only two.

Because of this, Adele never forgave Marc. During her Grammy acceptance speech, Adele proclaimed that she had lost all love for her dad.

In the world of music, very few singers can match Beyoncé’s talent, experience, and sheer work ethic. One of the reasons for her success, however, was her unrelenting father, Mathew Knowles. Their relationship throughout the years, as he managed Beyoncé’s music career, took a hit with tabloids picking up their story.

In 2011, the pair parted ways professionally but later on, reports lay blame on Mr. Knowles for allegedly skimming funds from Beyoncé. Things turned sour after he divorced Beyoncé’s mother after a 31-year marriage.

Kurt Cobain’s partner, Courtney Love, has been frank about her struggles with substance abuse and even admitted to how it affected her daughter, Frances Bean Cobain. After Kurt died in ’94, she was left alone to raise their daughter and failed spectacularly.

Her addiction got in the way of parenting and she openly confessed to using while pregnant with Frances. As a result, she lost custody of her daughter and the two have not patched things up since.

Christine Aguilera is a world-renown singer, actress, songwriter, and TV personality. The New York-born artist moved houses frequently because of her father’s military career.

Her dad, Aguilera points out, was abusive and violent towards the family, eventually leading to her parents’ divorce when she was only six. She then turned to her music career as a sort of escape from all the conflict surrounding her life.

Michael Jackson is another notable entry on this list. He is by far one of the most famous people on this planet and another musician whose parents took direct control over his music career. His father, Joe Jackson, did have a significant impact on his success. However, on the flip side, he was also known as an abusive dad.

The failed blues musician reigned terror upon his household and one might be inclined to believe that he was the root of all of Michael’s later scandals. From physical to mental abuse, Joe Jackson was content with any, as long as it served his purpose.

The “Daddy Issues” hit song maker hit the nail on the head with this tune. Since 2007, Demi Lovato and father Patrick Lovato have been at loggerheads. The two tried to reconcile their issues through the time but it seems Mr. Lovato wasn’t the ideal dad. The source of her estrangement from him was indeed himself and as Demi hinted, he always let down the only person who had faith in him.

And this proved to be his downfall. In 2013, Mr. Lovato died from cancer. A couple of Demi Lovato’s songs point to the strained relationship the father and daughter had. She released “For the Love of a Daughter” in the 2011 album Unbroken and “Father” in 2015’s Confident.

Kendra Wilkison, an American TV personality and glamor model, has seen her fair share of family feuds. Her parents’ marriage hit the rocks early in her life when she was just eight. After the separation, her dad vanished from her life.

Her grandmother also died in 2004, leaving Kendra with one less family member. In 2014, she reunited with her mom but the union was to be short-lived and the two are still estranged.

Leighton’s life started on the wrong foot from whichever angle you look at it from. Her mom, Constance Meester, was serving time when she was born for drug-related charges. After her release, they both had to live from hand-to-mouth. Leighton’s acting and modeling gigs helped bring some food to the table.

However, her mother was rarely cooperative or responsible, as she was supposed to be. She spent money meant for Leighton’s brother on her personal needs and in 2012, Leighton won a court case against her, stating that she just wanted Constance out of her life.

The screen siren has hosted several high profile shows ranging from Entertainment Tonight and MTV’s Total Request Live as well as a myriad of reality shows. Born to a Filipino mother and an American serviceman, Vanessa, and her family moved houses pretty much every year. She went to eight different schools in nine years.

Her parents eventually separated in 1983 and finally cut ties three years later. Both remarried, Vanessa spent time with each parent and their new spouse. She, however, left her mom to join her father in the US, and the two are reported to be on bad terms seeing as she did not bother to invite her mom to her wedding to Nick Lachey.

It is difficult to imagine someone having a fight with America’s sweetheart Meg Ryan and also a darling in Hollywood. Yet, Meg and her mother Susan are far from being the caring mother-daughter duo. Meg started her acting career in the 70s. She had a flourishing career and married a movie star.

Meg did not invite her mum to their wedding. This is because of her public criticism of Quaid and cut her out of her life. It is still uncertain whether there has been a reconciliation

Actress Kate Hudson has been estranged from her dad, Bill Hudson, for decades and this culminated in her father disowning her. Bill had five other children but disowned two of them in a public interview with Daily Mail in 2015. Kate’s brother, Oliver, also faced the same fate as his sister.

Oliver’s revenge, however, was well worth it after posting a photo of himself, Kate, and Bill on Instagram. The caption read “Happy Abandonment Day” on Father’s Day.

Parents often have a significant say in the type of career path we follow. Heather Graham’s parents were a religious bunch, and as is their upbringing, automatically opposed Heather’s participation in the film Boogie Nights.

However, it was the film that would eventually propel Heather to fame. She ultimately cut them out of her life ever since.

The magnificent Friends actress doesn’t seem like the kind of person who has family issues. However, things were never smooth sailing between her and mother Nancy Aniston. An actress herself, Nancy authored a book detailing her relationship with Jennifer titled From Mother and Daughter to Friends: A Memoir.

Because of this book, the two have been separated for nine years up until Jennifer’s divorce from Brad Pitt. They eventually reconciled their differences, and the younger Aniston even admitted that she was hopeful for the future. Nancy passed away in May 2016.

Rosie O’Donnell and her adopted daughter, Chelsea, have not been seeing eye-to-eye in recent years. The relationship between the two has been wrought with drama intermittently. Substance abuse has been the center of the conflict between the two, with Chelsea taking most of the blame.

In 2015, the 17-year old went missing and Rosie reported the matter only to find Chelsea at an alleged dealer’s home. Reconciliation followed, but as of 2017, their hostility was renewed as Chelsea married 31-year old Nicki Alliegro.

The O’Neal’s relationship with each other represents one of the worst cases of family disputes in this article. Theirs is marked by substance abuse and physical abuse, which soured the pair’s relationship even further. Tatum claims she received violent encounters with her father up until the time when she was pregnant.

The daughter, Tatum O’Neal, was the youngest person to grab an Oscar award in Hollywood and right off the bat you would expect her to be living one of the most comfortable and secure lives. However, the family unit is a bit different and up to today, the two have fruitlessly attempted to work on their relationship.

The Barrymore name is synonymous with Hollywood and acting. Drew has also made a name for herself in the industry and has received a couple of accolades along the way including the Golden Globe, a BAFTA nomination and a Screen Actors Guild Award.

Her childhood was, however, far from perfect due to her substance abuse and constant clubbing at the time. It prompted her to author a book at 16 aptly titled Little Girl Lost. Following her rehabilitation at 13, Drew Barrymore successfully filed for emancipation from her parents at 15.

Roseanne, an Emmy and Golden Globe award winner, began her career in showbiz doing standup comedy. This gradually progressed into acting and even a political career. She had a tumultuous youth when she was hit by a car causing her to be institutionalized at the Utah State Hospital for eight months at sixteen.

At 17, she had a child that she placed for adoption. When Roseanne turned 18, she moved out of her parents’ home. She has been estranged from her parents on the grounds of alleged physical abuse.

Kate Cassidy, daughter to actor David Cassidy, is famous for her role in Arrow as the ‘Black Canary.’ David’s relationship with Katie’s mother, actress Sherry Williams, was brief and that was pretty much the father-daughter relationship as well.

The young actress was then raised by mom and stepdad, Richard Benedon. Following his death, it was revealed that Katie Cassidy was not included in her biological father’s last will. This goes to show how much Mr. Cassidy thought of Katie.

Not much is known about Ariana and her dad’s relationship. However, in her single Thank U Next, Ariana happens to sing with warmth towards her mother but not her dad.

This points to a rift between the two. Although the celebrated singer has rarely opened up about their relationship, she did state that it all started in 2013. Ariana is currently estranged from her dad.

Modern Family has received critical acclaim, and this has mainly been attributed to the Winter’s family acting prowess. However, do not let their success fool you into thinking these guys have it all. Ariel, for one, had to deal with a lot of adult issues from a young age.

While 13, she was forced out of her mother, Chrisoula Workman’s, home over physical abuse allegations. This prompted her to seek emancipation from Chrisoula, and in May 2015, her wish was granted. She then took to social media to celebrate this new milestone in her life.

Mackenzie Philips’s relationship with her dad is perhaps the most saddening on this list. It has been pockmarked with cases of sexual, mental, and physical abuse that stemmed from her father. After the sexual abuse, she confronted him after which he dismissed the incident as consensual ‘lovemaking.’

For some reason, Mackenzie opted to tour with her dad’s band and this fueled her indulgence with drugs and incest with her dad. On his deathbed, she forgave her father but now took up drugs as the next course of action. Despite being born into a Hollywood family, Philips’ life has been far from glamorous.

As far as family feuds go, Gary Coleman’s separation from his parents went in his favor. The Different Strokes star, despite having an illustrious childhood acting career, was left broke. This occurred after he made payments to his parents, advisers, and other associates.

Coleman then proceeded to sue his parents for $1.3 million on the grounds of misappropriating his funds. Coleman scored a big win over his folks from the lawsuit.

Best known for his role in the boyband Backstreet Boys, Nick’s relationship with his parents was strained from the beginning. He alleges that he started abusing alcohol from a very early age and eventually came to suffer from it. He was diagnosed with cardiomyopathy, and doctors advised him to make drastic lifestyle changes or face death.

Following his sister’s death due to a substance overdose, the family lay blame on Nick because of his past drug use and fell apart soon after.

Surprisingly, Selena Gomez is on this list partly because of her previous relationship with Justin Bieber. Remember how parents have a say in practically all aspects of our lives; celebrity parents are hardly left behind when it comes to parenting matters. Family sources indicate that Selena’s mom, Mandy Teefey, was hardly pleased with the news of her daughter and Justin seeking relationship assistance.

That is not all, however, as the two have been at it on social media with the pair unfollowing each other on Instagram. The root of all this conflict seems to be Selena’s decision to drop Mandy as her manager.

Technically, only Justin Bieber is the celebrity here. But even so, Justin Bieber’s relationship with mom Pattie Mallette has seen its fair share of ups and downs. Justin admitted that theirs was pretty much absent.

He went on to further concede his fear of the supposed shame he bore, mainly drawn from his scandals in the public limelight. Nevertheless, the two seemed to have reconciled their differences as Pattie Mallette gushed over her son while on vacation in the Maldives.

Macaulay Culkin

Christmas film favorite Macaulay Culkin is a critically acclaimed actor, more so when he was a child. The Home Alone movie series had holidaymakers glued to their screens throughout the festive season with Macaulay’s antics.

However, things weren’t always rosy back at the Culkin household. 1995 saw his parents’ divorce and contest custody of their seven children, especially now that Macaulay was already making inroads into Hollywood. The dad, however, was an alcoholic and violent adulterer, according to Patricia Brentrup, Macaulay’s mom. Kit Macaulay eventually disowned Macaulay as his son in the Daily Mail.

Caitlyn Jenner

Drama and scandals have been at the center of the Kardashian family. Some people believe it is what brought them the fame that they enjoy so much today. Caitlyn, who once fathered the Kardashian offspring, is now estranged from the entire group. The first falling out occurred with the Kardashian matriarch Kris Jenner.

This spread conflict onto her daughters and Caitlyn’s estranged son Brody. Brody confronted Caitlyn about his absence from his childhood life, to which the senior Jenner declined to comment on the issue.

Sheri Shepherd

Sherri Shepard’s estrangement debacle was one of the oddest at the time. Following her divorce to ex-husband Lamar Sally, Sherri wanted to overturn custody of their unborn child over to him.

This was because since the two had planned for a surrogate to bear the child, Sherri was technically not the biological mother to the child. Therefore, she argued that the child ought to be with the dad, Mr. Sally. However, her grievances fell on deaf ears as the court declined to abide by her wishes.